Use this medication only as directed by your veterinarian.
Consult your veterinarian about the proper technique
for administering injectable medications.
Dose as prescribed. Do not differ from the dosing
schedule given by your veterinarian.
Intramuscular Injection Directions:
- Give dogs the dose prescribed by your veterinarian.
The typical dose for dogs ranges from 2 mg in miniature breeds to 40
mg in medium breeds. Larger dogs may require even larger doses.
- Give cats the amount prescribed by your veterinarian.
The usual dose for cats is 10 mg to 20 mg. Dose weekly or as prescribed.
- Give horses the amount prescribed by your veterinarian.
The typical dose for horses is 200 mg, as needed.
Intrasynovial Injection Directions:
- Follow the injection preparation procedure prescribed
by your veterinarian.
- Dose based on the size of the synovial space and
animal.
- Give dogs the dose prescribed by your veterinarian.
The average dose for a large synovial space is 20 mg.
- Give horses the dose prescribed by your veterinarian.
The average dose for a large synovial space is 120 mg.
Frequency of Use:
The duration of treatment depends on the animal and
condition being treated, the severity of illness, and the individual
response. When stopping long-term use, reduce the dose gradually to
avoid potentially serious withdrawal effects.
Storage:
Store Depo-Medrol at room temperature, in a light-resistant
and childproof container. Keep away from pets and children.
It is a violation of Federal
Law to use this product in a manner inconsistent with its labeling.
Depo-Medrol contains methylprednisolone, a synthetic
steroid with anti-inflammatory properties that is a derivative of prednisolone.
It works by blocking production of substances in the body that trigger
inflammation and allergic reactions.
Ingredients (20 mg per mL): Methylprednisolone acetate 20 mg, Polyethylene
glycol 3350 29.6 mg, Sodium chloride 8.9 mg, Myristyl-gamma-picolinium
chloride (added as preservative) 0.198 mg
Ingredients (40 mg per mL): Methylprednisolone acetate 40 mg, Polyethylene
glycol 3350 29 mg, Sodium chloride 8.7 mg, Myristyl-gamma-picolinium
chloride (added as preservative) 0.195mg
Warnings:
Keep this product out of reach of children and animals.
Do not use or store in or near open flame or heat.
Depo-Medrol is intended for use in dogs, horses,
and cats only. Not for other animals or for humans.
CAUTION: Side effects of Depo-Medrol
may include increased thirst, appetite, and urination. Weight gain,
diarrhea, behavior changes, vomiting, and panting are other common side
effects. Long-term use may result in weakness, muscle loss, diabetes,
Cushing's disease, and/or pancreatitis.
Pets taking this medication may experience immune
system suppression, putting them at greater risk for infection.
Do not stop giving this medication abruptly. Doing
so may cause weakness, vomiting, collapse, or sudden death.
Tell your veterinarian about any over-the-counter
or prescription medications your pet is taking before beginning treatment
with Depo-Medrol.
Use of Depo-Medrol may cause abnormal levels of thyroid
hormone, potassium, hepatic enzymes, or cholesterol. This may affect
laboratory testing.
Do not give this medication to animals with tuberculosis,
Cushing's syndrome, congestive heart failure, osteoporosis, diabetes,
or hypertension without first consulting your veterinarian.
Do not use in pregnant or breeding animals.
Do not use this medication in animals with a known
allergy to it or to similar medications.
Warranty and Manufacturer Information:
Caution: Federal (USA) law restricts this drug to
use by or on the order of a licensed veterinarian.
NADA No.: 012-204, Approved by FDA
Pharmacia & Upjohn Company, Kalamazoo, Michigan
49001, USA
Revised October 1997
811 350 108
691272
NAC No.: 10490130